It is a major cause of pneumonia in young age groups (5-20yrs.) Extra pulmonary manifestations: Hemolytic anemia Skin rashes/lesions Meningoencephalitis Myelitis Neuritis Myopericarditis Arthritis
Specimen: Sputum Culture: Cultured in semisolid media-enriched with yeast extract and serum, incubated aerobically for 7-12 days Identification: Observe for “fried-egg” colonies embedded into the surface of the medium or inhibition of growth around discs impregnated with specific antisera.
Serology: Complement fixation test Indirect Immunofluorescent test Haemagglutination inhibition test
NB: Cold hemagglutinins titier infection Treatment: Tetracycline
1:64 suggests M.pneumoniae
NB: The above antibiotics produc eclinical improvement but do not eradicate the organism