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STUDY DESIGN

Non-emergent PCI : ACS and Stable angina (n=406)

Loading dose (LD)   ASA 250mg

VASP ≥ 50%

Randomization

(n=162)

CONTROL (n=84)

VASP-guided LD (n=78)

Up-to 3 additional LD of 600 mg every 24 hours until VASP < 50% before PCI

Maintenance dose  ASA 160 mg Clopidogrel 75 mg

1° endpoint: MACE (CV death, MI, revascularization) at 30 days

2° endpoints: TIMI major and minor bleeding at 30 days

Bonello et al. J Am Coll Cardiol 2008

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