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Drugs and molecules that modulate DA transmission

1) phenylalanine: amino acid that can be converted to tyrosine by

enzyme phenylalanine hydroxylase. 2) alpha-methyl-p-tyrosine: blocks tyrosine hydroxylase. 3) carbidopa: __________________________________________ 4) reserpine: ______________________________________. 5) conotoxin: voltage-gated Ca++ channel blocker. 6) bromocriptine, pergolide: ________________________________. 7) haloperidol: D2 dopamine receptor antagonist. 8) amphetamine, cocaine, methylphenidate: block reuptake of DA into .

presynaptic terminal (also facilitate release from synaptic vesicles). 9) deprenyl: inhibitor of monoamine oxidase type B.

Draw a synapse, with all components involved in DA transmission.

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