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The Biology of Malnutrition - page 10 / 31

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Thiamin Deficiency and Refeeding

Deficiency may contribute to refeeding syndrome

Functions as a cofactor in intermediary carbohydrate metabolism

Amount needed depends on carbohydrate ingested, so feeding carb without adequate thiamin supplementation can lead to deficiency symptoms

Mental confusion, ataxia, muscle weakness, edema, muscle wasting, tachycardia and cardiomegaly

Wernicke’s encephalopathy can be precipitated by carbohydrate feeding in thiamine-deficient patients

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