OECD SIDS 5. TOXICITY
ID: 79-50-5 DATE: 18.01.2006
the study in the case of the females, while the males were killed after 28 days so that potential recovery could not be assessed. Reproductive, breeding and developmental parameters were unaffected up to 1000 mg/kg bw/d. Based on the results in this combined repeated dose toxicity
study with reproduction/developmental screening test, definitive suc-chronic parental NOAEL was established
200 mg/kg bw/d. The definitive reproductive,
the as being and
developmental NOAEL was established as being 1000 mg/kg bw/d.
valid without restriction
OECD test under GLP. Critical study for SIDS
Toxicity to Reproduction, Other Studies
5.11 Additional Remarks
ile on Pantola DL-, D- or un against the e agents". Spec or inability t s exposed to u
ctone states, "Numerous defined pantolactone can ffects (often genotoxic) ifically, dl-lactone o divide normally in ltraviolet radiation or
tions orts in peer-r s regarding an capabilities o t 2.
eviewed literature, all timutagenic respectively f (dl-)lactone, hence
Biochemical or cellular
The BIBRA Toxicity Prof
studies have shown that protect micro-organisms of certain chemicals or restituted the ability Escherichia coli mutant thermal treatment.
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