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DL-LACTONE CAS N°:79-50-5 - page 56 / 113

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OECD SIDS 3. ENVIRONMENTAL FATE AND PATHWAYS

DL-LACTONE

ID: 79-50-5 DATE: 18.01.2006

GLP: Test substance:

no as prescribed by 1.1 - 1

Result:

Bioconcentration factor BCF fish 1 (pH 1-10) 3.162 0 1.41 0.05

.4

Source

SciFinder (ACD Solaris V4.67) EPISuite v3.11 (BCF v2.15) ChemSCORER beta100 USES 4.02 calculated, Veith et al. (1979): logBCF = 0.85*logPow - 0.70

Conclusion:

Reliability:

Bioaccumu (sum of B 0 Based on consisten bioaccumu An additi incorpora biomagnif nonsignif

(2)

vali

lation factor CF and biomagni

four modelled b tly below 5, dl late to a signi onal modelled b ted both biocon ication from th icant bioaccumu d with restrict

fication factor), fish ChemSCORER beta100 ioconcentration factors, which are

  • -

    lactone is not expected to

ficant degree. ioaccumulation factor, that centration from the medium and e food chain, also suggests lation. ions

Flag: 11-MAR-2005

Accepted

QSAR programmes

Critical

study for SIDS

and regression equation. endpoint

(13) (20) (44)

(60)

(61)

Species: BCF:

other: earthworm model ca. .84 - 3.23

Method:

Year: GLP: Test substance:

other: QSAR calculated 2004 no as prescribed by 1.1 - 1.4

Method:

USES 4.02. Basic physicochemical data for entered into the respective USES fields an --- EU TGD, Connell & Markwell: The Kow of dl- outside the range based on which the regre hence the minimum of logKow = 1 was used a --- EU TDG, Jager: BCF(earthworm) = (0.84 + 0.012*Kow)/RHO(ea

dl-lactone d the mode

lactone (0 ssion is b s a defaul

rthworm)

were l was run.

.204) is ased, t value.

Remark:

= (0.81 + 0.012*0.204)/1 [RHO(earthworm) default value = 1] Connell & Markwell derived the empirical e regression on experimental data for pestic ranging from 1.0 to 6.5. Since the logKow

isoutside this range (-0.69 <=> Kow

= 0.20

quation th ides with of dl-lact 4) the min

orugh a logKow one imum

Result:

logKow of 1 was used as Bioconcentration factor for earthworms

a default. Source

Conclusion:

---------- 3.23 kg/kg

1

kg/kg

0.84 kg/kg

------------------------------------------ USES 4.02 EU TGD; based on Connell & Markwell (1990) EU TGD; based on Jager (19

---------------------------------------------------- Based on three modelled bioconcentration factors, dl is not expected to bioaccumulate in earthworms from

---

98) ---

  • -

    lactone

soil or

56

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