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DL-LACTONE CAS N°:79-50-5 - page 64 / 113

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OECD SIDS 4. ECOTOXICITY

DL-LACTONE

ID: 79-50-5 DATE: 18.01.2006

Test substance:

Conclusion:

78 mg/l. At 100 mg/ exposure c significan controls. respective an ErC50 n effects. dl-Lactone according dl-Lactone standard t

l nominal or starting concentration and an average oncentration of 78 mg/l over 72 h, dl-lactone had no t effect on biomass and growth rate compared to The NOEC was 100 mg/l nominal concentration ly 78 mg/l average exposure concentration, neither or an EbC50 could be determined due to lack of

from Roche Dalry, batch 805046, purity 100.0% to certificate of analysis.

had no inhibitory effect on green algae in a est over 72 h at a nominal concentration of 100 mg/l

and an average measured concentration of 78 mg/l.

In a comparison of algal-free vessels

dl-lactone concentrations in algal

at

100

mg/l

nominal

concentration

and

after

72

h,

enhanced

degradation

was

seen

in

the

algal

vessels,

which

suggests that the algae were actively degrading dl-lactone

to

an unidentified metabolite.

Reliability:

(1) OECD

valid without restriction test under GLP with analytical

confirmation.

Flag: 16-NOV-2005

Critical

study

for

SIDS

endpoint

(9)

Species:

Scenedesmus subspicatus

Exposure period:

72 hour(s)

Unit:

mg/l

EC10:

- measured/nominal

EC50:

> 100 -

(Algae)

Analytical monitoring: no data

Method: GLP: Test substance:

other: DIN 38412 part 9 no data other TS

, static

Remark:

Result:

Test substance:

No further data on meth characteristics of the is being cited as suppo In a safety data sheet isomers in dl-lactone) toxicity of D-pantolact mg/l (nominal concentra concerns the biomass or both. Crystalline D-pantolact (communication from BAS

od, year or GLP due to the source, a safety data sheet. The result rtive evidence. for D-pantolactone (one of the two from BASF Company in Germany, the acute one to green algae is stated as >100 tion); it is not specified whether this

growth rate endpoint or, probably,

one, CAS 599-04-2, purity 99% F, 26-Aug-2004).

Reliability:

(4) The

not assignable safety data sheet

r

source

without any expe

safety

data sheets.

eceived from BASF is only a condensed rimental details, as is typical for

30-JUN-2005

(3)

4.4 Toxicity to Microorganisms e.g. Bacteria

Type: Species:

other: ready biodegradation test toxicity/inhibition control activated sludge of a predominantly domestic sewage

Exposure period:

14 day(s)

Unit: NOEC:

mg/l

Analytical monitoring: yes

>= 22 - measured/nominal

Method:

other: OECD Guideline 301B, toxicity control

64

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