OECD SIDS 4. ECOTOXICITY
ID: 79-50-5 DATE: 18.01.2006
78 mg/l. At 100 mg/ exposure c significan controls. respective an ErC50 n effects. dl-Lactone according dl-Lactone standard t
l nominal or starting concentration and an average oncentration of 78 mg/l over 72 h, dl-lactone had no t effect on biomass and growth rate compared to The NOEC was 100 mg/l nominal concentration ly 78 mg/l average exposure concentration, neither or an EbC50 could be determined due to lack of
from Roche Dalry, batch 805046, purity 100.0% to certificate of analysis.
had no inhibitory effect on green algae in a est over 72 h at a nominal concentration of 100 mg/l
and an average measured concentration of 78 mg/l.
In a comparison of algal-free vessels
dl-lactone concentrations in algal
suggests that the algae were actively degrading dl-lactone
an unidentified metabolite.
valid without restriction test under GLP with analytical
> 100 -
Analytical monitoring: no data
Method: GLP: Test substance:
other: DIN 38412 part 9 no data other TS
No further data on meth characteristics of the is being cited as suppo In a safety data sheet isomers in dl-lactone) toxicity of D-pantolact mg/l (nominal concentra concerns the biomass or both. Crystalline D-pantolact (communication from BAS
od, year or GLP due to the source, a safety data sheet. The result rtive evidence. for D-pantolactone (one of the two from BASF Company in Germany, the acute one to green algae is stated as >100 tion); it is not specified whether this
growth rate endpoint or, probably,
one, CAS 599-04-2, purity 99% F, 26-Aug-2004).
not assignable safety data sheet
without any expe
eceived from BASF is only a condensed rimental details, as is typical for
4.4 Toxicity to Microorganisms e.g. Bacteria
other: ready biodegradation test toxicity/inhibition control activated sludge of a predominantly domestic sewage
Analytical monitoring: yes
>= 22 - measured/nominal
other: OECD Guideline 301B, toxicity control