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DL-LACTONE CAS N°:79-50-5 - page 65 / 113

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OECD SIDS 4. ECOTOXICITY

DL-LACTONE

ID: 79-50-5 DATE: 18.01.2006

Year: GLP: Test substance:

2004 yes as prescribed by 1.1 - 1.4

Result:

Beside the standar 40 mg sodium aceta biodegradation mea single vessel was activated sludge/l adsorption by DOC. plateau of 79% DOC to the standard CO strong adsorption.

d toxcity control with 22 mg dl-lactone/l, te/l and 30 mg activated sludge/l and surement by carbon dioxide evolution, a run with 100 mg dl-lactone/l and 1000 mg

in order to measure short-term (3-hour) Following this vessel over longer time, a removal was reached from day 16, parallel 2 test vessels, without any evidence for

This was taken as further evidence for easy

Test substance:

biodegradability and for low toxicity towards bacteria. Hence the formulation of NOEC >= 22 dl-Lactone from DSM (until 2003 Roche) Dalry,

activated sludge mg/l. sample no.

06085776, purity 99.6%, dated 24-Sep-2004.

Reliability:

(1)

valid without restriction

Flag: 10-MAR-2005

Test according Critical study

to OECD guideline for SIDS endpoint

under

GLP.

(18)

Type: Species: Exposure period: Unit: NOEC:

other: activated sludge bacteria activated sludge, domestic

21 day(s) mg/l

Analytical monitoring: no

= 1000 - measured/nominal

Method:

Year: GLP: Test substance:

other: comparable to OECD Guide-line 302 B 1983 no as prescribed by 1.1 - 1.4

Method:

A standard inherent degradation test was performed with pure dl-lactone from lab production in a Sapromat respirometer in a

Result:

Test substance: Conclusion:

test setup corresponding to OECD 30 activated sludge was a 1:1 mixture municipal sewage works and from the treatment plant receiving a continu sample of industrial wastewater. Te 100 and 1000 mg dl-lactone/l. Degra oxygen consumption and compared to calculated as percent degradation. Degradation for both 10, 100 and 10 99% in 21 days. There was no inhibi bacteria in the presence of 10, 100 dl-Lactone from Roche, "pure", not dl-Lactone was not inhibitory to no bacteria in a respirometric inheren

2C, except that the (w/w) from a single small

in-house pilot wastewater ous flow-proportional st concentrations were 10, dation was followed by the COD for dl-lactone and

00 mg dl-lactone/l reached tion of activated sludge

or 1000 mg dl-lactone/l. otherwise characterised. n-adapted activated sludge t biodegradability test up

to a starting concentration of 1000 mg/l.

Reliability:

(2)

valid with restrictions

Biodegradability

and

inhibition

assessment

from

the

in-house

Flag: 10-MAR-2005

wastewater lab, not GLP professional laboratory Critical study for SIDS

but highly standardised test in with many years of experience. endpoint

a

(24)

Type:

aquatic

Species:

activated sludge

Exposure period:

30 minute(s)

UNEP PUBLICATIONS

65

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