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P R O C E E D I N G S

(8:29 a.m.)

DR. KIBBE:  Ladies and gentlemen, I want to welcome you to the second day of the meeting.

If the members of the committee will make sure they're in position and we'll get started.  We have an extremely busy day.  We have lots of presenters during the open discussion.  So we need to be efficient, if at all possible.

Ms. Reedy will read a statement on conflict of interest.

MS. REEDY:  Acknowledgement related to general matters waivers, Advisory Committee for Pharmaceutical Science on March 13th, 2003, the open session.

The following announcement addresses the issue of conflict of interest with respect to this meeting and is made a part of the record to preclude even the appearance of such at this meeting.

The topics of this meeting are issues of broad applicability.  Unlike issues before a committee in which a particular product is discussed, issues of broader applicability involve many industrial sponsors and

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