intervals and point estimates for the amount of potassium excreted in the 24-hour interval after dosing for formulation A. The ratios for this parameter fell within the 80 to 125 goal post for the 90 percent confidence intervals. However, with baseline correction, the 90 percent confidence interval was wider than with uncorrected data.
As I mentioned earlier for this particular product, formulation A, without baseline correction, the test-to-reference ratios for Rmax, the maximal rate of excretion, fell within 80 to 125. When we did the baseline correction, the lower bound of the 90 percent confidence interval for Rmax was outside of the 80 to 125 range.
Then what we did was we compared two different methods of baseline correction to see if there was a difference in the results. We subtracted the mean excretion rate from the corresponding interval and that's the usual way of correcting for potassium chloride excretion, as I discussed earlier. We also subtracted the overall mean excretion rate from the 2 baseline days and we found that the outcome was the same, regardless which