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Considerations for Exposure to Diazinon and Chlorpyrifos - page 23 / 49

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Injected PON1 Protects Against OP Exposure

The next slide shows the results of dermal exposure to chlorpyrifos oxon (CPO, 14 mg/kg) of mice injected with purified rabbit PON1 compared with mice not receiving purified rabbit PON1.  It is clear from the slide that high levels of plasma PON1 provided excellent protection against cholinesterase inhibition in the brain and diaphragm.

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